Two different aldolase A mRNA species in rat tissues
نویسندگان
چکیده
منابع مشابه
Expression of two aldolase A mRNA species in different human and rat tissues
The development stageand tissue-specific expression of multiple mRNAs encoding a same protein is now a welldocumented phenomenon (Schibler et al., 1983; MacGrogan et al., 1985). Recently, it has been shown in rat (Mukai et al., 1984; Tsutsumi et al., 1984) that aldolase A is translated from two mRNAs, of 1650 and 1550 bases; the latter was detected in adult muscle, whereas the former was presen...
متن کاملRegulation of 5-aminolevulinate synthase mRNA in different rat tissues.
cDNA clones for rat liver 5-aminolevulinate synthase have been isolated and used to examine mRNA levels in different rat tissues. Northern hybridization analysis of total RNA from various rat tissues showed the presence of a single 5-aminolevulinate synthase mRNA species of estimated length 2.3 kilobases. Primer extension and RNase mapping studies indicated that the mRNA is identical in all tis...
متن کاملDetermination of aldolase in animal tissues.
Aldolase catalyzes the reversible cleavage of 1 mole of fructose-l ,6diphosphate (HDP) into 1 mole of glyceraldehyde-3-phosphate and 1 mole of dihydroxyacetone phosphate (1, 2). Although the enzyme has been obtained in crystalline form by Warburg and Christian (3) and by Taylor, Green, and Cori (4) only fragmentary data concerning the content of aldolase in different mammalian tissues have been...
متن کاملProhibitin 2 mRNA downregulation in breast cancer tumor tissues
Introduction: Breast cancer is the most important cause of cancer mortality among women, therefore the study of its causative or aggravating factors seems necessary. In this study, the mRNA levels of the PHB2 gene were evaluated in tumor and adjacent non-tumor tissues of 50 women diagnosed with invasive ductal carcinoma of the breast. Methods: RNX-Plus solution was used to isolate total RNA fro...
متن کاملGrowth hormone induces two mRNA species of the serine protease inhibitor gene family in rat liver.
In order to study the molecular actions of growth hormone on gene expression, we have cloned and characterized two unique, but related, cDNA sequences from rat liver, lambda Spi-1 and lambda Spi-2. These two cDNA sequences are complementary to rat hepatic mRNA species previously designated as Spots 3 and 20 when assayed by in vitro translation and two-dimensional gel electrophoresis. By Norther...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1984
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1984.tb08264.x